Skip to main content
Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Analysis of microbial differences in amniotic fluid between advanced and normal age pregnant women

Fig. 1

Differences between the normal and AMA AF samples in species composition and structure of communities. A Detected compositions and relative abundances of bacterial communities according to 16S rRNA gene sequencing. The normal age (left) and AMA (right) bacterial relative abundances of the top 10 bacterial communities were labeled with different colors. Unclassified: unclassified bacterial communities; others: other bacterial communities. B Comparison of distance indexes indicating species composition and structure of communities between the normal and AMA groups. (Weighted_unifrac, Welch’s t test, P  =  0.017). C Circular cladogram indicating the polygenetic distribution of the bacterial lineages in the AF samples from the normal and AMA groups as determined by the linear discriminant analysis (LDA) effect size (LEfSe) (right) and comparison of the LDA effect size of the significantly different bacterial taxa (left). The cladogram illustrates the phylogenetic relationships among the significantly different bacterial taxa. The dots in the center represent the OTUs at the phylum level, while the dots in the outer circle represent the OTUs at the species level. Coloring principles: species with no significant difference were uniformly colored yellow; species for biomarkers were colored according to the different groups, with red nodes indicating bacteria with important roles in the AMA group, and green nodes indicating bacteria with important roles in the normal group. The names of the species represented by a, b, c, d, and e in the figure are shown in the LDA score illustration on the right. Indicators were defined as those with LDA  >  4. The histogram shows the LDA scores computed for significantly abundant taxa between the normal and AMA groups. The histogram represents the most significantly abundant taxa between the two groups. AMA: bacterial groups in the AMA group; normal: bacterial groups in the normal group

Back to article page