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Table 9 Identified scalp stimulation targets for ADHD

From: Potential scalp stimulation targets for mental disorders: evidence from neuroimaging studies

Cluster ID

Cluster size

Peak T

Peak coordinates

Brain regions

10–20 EEG system locations

Acupoint locations

Functions

x

y

z

ADHD-1

188

6.98

− 48

10

32

L IFG/dlPFC/mPFC/PreCG

1 cm posterior and inferior to F3

0.6 cun posterior and superior to GB 4

Planning complex, coordinated movements

ADHD-2

205

8.62

− 36

22

− 8

L IFG/OrbIFG

1 cm posterior and inferior to F7

0.6 cun inferior to GB 5

Language processing and comprehension, emotional recognition

ADHD-3

120

6.98

− 40

− 56

46

L IPL/PCu/AG

P3

GB 18

Sentence generation, arithmetic learning, abstract coding of numerical magnitude, spatial focusing of attention, performing verbal creative tasks, processing a sequence of actions

ADHD-4

236

8.62

− 2

20

42

L MedFG/SupMFG/mPFC

Midpoint of Fz and Cz

0.1 cun posterior to GV 22

Motor learning/imagery/control, executive control of behavior, language processing, working memory, visuospatial and visuomotor attention, pain anticipation

ADHD-5

81

6.98

36

26

40

R MFG/dlPFC/mPFC

1 cm superior to F4

0.3 cun inferior to BL 5

Planning complex movements

ADHD-6

168

6.98

36

24

8

R IFG/TriIFG

1 cm posterior to F8

Midpoint of GB 5 and GB 6

Semantic tasks (decision/generation/retrieval/working memory processes)

ADHD-7

99

6.15

58

− 46

30

R IPL/SMG

2 cm anterior and inferior to P4

0.6 cun anterior and inferior to GB 18

Reading, spatial focusing of attention, visuospatial processing

ADHD-8

105

6.98

− 2

50

− 10

L MedFG/OrbMFG

Midpoint of Fp1 and Fp2

0.6 cun anterior to GV 24

Working memory, episodic memory, and multiple-task coordination

ADHD-9

82

6.15

− 28

− 54

42

L SPL/IPL/PCu

1 cm lateral to P3

0.3 cun medial and superior to GB 9

Sentence generation, arithmetic learning, abstract coding of numerical magnitude, spatial focusing of attention, performing verbal creative tasks, executive control of behavior

  1. L, left; R, right; MFG, middle frontal gyrus; IFG, inferior frontal gyrus; OrbIFG, orbital inferior frontal gyrus; SupMFG, superior medial frontal gyrus; MedFG, medial frontal gyrus; OrbMFG, orbital medial frontal gyrus; TriIFG, triangular inferior frontal gyrus; dlPFC, dorsolateral prefrontal cortex; mPFC, medial prefrontal cortex; SPL, superior parietal lobule; IPL, inferior parietal lobule; SMG, supramarginal gyrus; AG, angular gyrus; PreCG, precentral gyrus; PCu, precuneus; cm, centimeter; cun, Chinese inches, 1 cun is about 3.33 cm; GV 22, Xinhui; GV 24, Shenting; GB 4, Hanyan; GB 5, Xuanlu; GB 6, Xuanli; GB 9, Tianchong; GB 18, Chengling; BL 5, Wuchu