|
Characteristics
|
Development set (n = 546)
|
Temporal validation set (n = 195)
|
P values
|
|---|
|
Diagnosis of post-LT AKI
|
301 (55.13%)
|
98 (50.26%)
|
0.867
|
|
Demographics
|
|
Gender (male, n)
|
472 (86.45%)
|
171 (87.69%)
|
1
|
|
Age (y)
|
50.61 (10.76)
|
47.02 (10.07)
|
< 0.001
|
|
Height (cm)
|
167.77 (9.55)
|
168.55 (6.42)
|
0.292
|
|
Weight (kg)
|
64.25 (11.42)
|
65.13 (11.14)
|
0.35
|
|
BMI
|
22.71 (3.33)
|
23.09 (3.06)
|
0.164
|
|
Predicting variables
|
|
IBIL (μmol/L)
|
90.34 (97.04)
|
96.91 (109.27)
|
0.433
|
|
UO (ml/(kg*h))
|
3.09 (2.2)
|
3.03 (1.99)
|
0.73
|
|
Time under GA(min)
|
543.0 (121.0)
|
498.86 (111.18)
|
< 0.001
|
|
PLT(109/L)
|
94.45 (80.83)
|
93.89 (76.62)
|
0.932
|
|
Steatosis grade ≥ 1
|
147 (26.92%)
|
85 (43.59%)
|
0.001
|
|
Preoperative LOS (d)
|
18.23 (21.82)
|
15.78 (21.13)
|
0.175
|
|
EBL (ml)
|
2066.38 (1906.18)
|
1559.1 (1918.04)
|
0.002
|
|
ALB (g/L)
|
35.56 (4.89)
|
34.74 (6.96)
|
0.133
|
|
Bicarbonate (ml)
|
124.04 (211.47)
|
169.92 (203.77)
|
0.009
|
|
Colloid (ml)
|
111.24 (301.53)
|
32.31 (117.68)
|
< 0.001
|
|
Pre-operative HE (n)
|
129 (23.63%)
|
37 (18.97%)
|
0.899
|
|
Cryoprecipitate(U)
|
30.46 (16.03)
|
26.53 (15.13)
|
0.003
|
|
ALT (U/L)
|
131.08 (433.19)
|
72.26 (211.4)
|
0.069
|
|
Pre-operative HM (n)
|
209 (38.28%)
|
91 (46.67%)
|
0.249
|
- AKI, acute kidney injury’; IBIL, indirect bilirubin; UO, urine output; GA, general anesthesia; PLT, platelets; LOS, length of stay; EBL, estimated blood loss; ALB, albumin; HE, hepatic encephalopathy; ALT, alanine transaminase; HM, hepatic malignancy
