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Table 2 Comparison of development set and the temporal validation set

From: An explainable supervised machine learning predictor of acute kidney injury after adult deceased donor liver transplantation

Characteristics

Development set (n = 546)

Temporal validation set (n = 195)

P values

Diagnosis of post-LT AKI

301 (55.13%)

98 (50.26%)

0.867

Demographics

 Gender (male, n)

472 (86.45%)

171 (87.69%)

1

 Age (y)

50.61 (10.76)

47.02 (10.07)

 < 0.001

 Height (cm)

167.77 (9.55)

168.55 (6.42)

0.292

 Weight (kg)

64.25 (11.42)

65.13 (11.14)

0.35

 BMI

22.71 (3.33)

23.09 (3.06)

0.164

Predicting variables

 IBIL (μmol/L)

90.34 (97.04)

96.91 (109.27)

0.433

 UO (ml/(kg*h))

3.09 (2.2)

3.03 (1.99)

0.73

 Time under GA(min)

543.0 (121.0)

498.86 (111.18)

 < 0.001

 PLT(109/L)

94.45 (80.83)

93.89 (76.62)

0.932

 Steatosis grade ≥ 1

147 (26.92%)

85 (43.59%)

0.001

 Preoperative LOS (d)

18.23 (21.82)

15.78 (21.13)

0.175

 EBL (ml)

2066.38 (1906.18)

1559.1 (1918.04)

0.002

 ALB (g/L)

35.56 (4.89)

34.74 (6.96)

0.133

 Bicarbonate (ml)

124.04 (211.47)

169.92 (203.77)

0.009

 Colloid (ml)

111.24 (301.53)

32.31 (117.68)

 < 0.001

 Pre-operative HE (n)

129 (23.63%)

37 (18.97%)

0.899

 Cryoprecipitate(U)

30.46 (16.03)

26.53 (15.13)

0.003

 ALT (U/L)

131.08 (433.19)

72.26 (211.4)

0.069

 Pre-operative HM (n)

209 (38.28%)

91 (46.67%)

0.249

  1. AKI, acute kidney injury’; IBIL, indirect bilirubin; UO, urine output; GA, general anesthesia; PLT, platelets; LOS, length of stay; EBL, estimated blood loss; ALB, albumin; HE, hepatic encephalopathy; ALT, alanine transaminase; HM, hepatic malignancy