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Table 2 Comparison of development set and the temporal validation set

From: An explainable supervised machine learning predictor of acute kidney injury after adult deceased donor liver transplantation

Characteristics Development set (n = 546) Temporal validation set (n = 195) P values
Diagnosis of post-LT AKI 301 (55.13%) 98 (50.26%) 0.867
Demographics
 Gender (male, n) 472 (86.45%) 171 (87.69%) 1
 Age (y) 50.61 (10.76) 47.02 (10.07)  < 0.001
 Height (cm) 167.77 (9.55) 168.55 (6.42) 0.292
 Weight (kg) 64.25 (11.42) 65.13 (11.14) 0.35
 BMI 22.71 (3.33) 23.09 (3.06) 0.164
Predicting variables
 IBIL (μmol/L) 90.34 (97.04) 96.91 (109.27) 0.433
 UO (ml/(kg*h)) 3.09 (2.2) 3.03 (1.99) 0.73
 Time under GA(min) 543.0 (121.0) 498.86 (111.18)  < 0.001
 PLT(109/L) 94.45 (80.83) 93.89 (76.62) 0.932
 Steatosis grade ≥ 1 147 (26.92%) 85 (43.59%) 0.001
 Preoperative LOS (d) 18.23 (21.82) 15.78 (21.13) 0.175
 EBL (ml) 2066.38 (1906.18) 1559.1 (1918.04) 0.002
 ALB (g/L) 35.56 (4.89) 34.74 (6.96) 0.133
 Bicarbonate (ml) 124.04 (211.47) 169.92 (203.77) 0.009
 Colloid (ml) 111.24 (301.53) 32.31 (117.68)  < 0.001
 Pre-operative HE (n) 129 (23.63%) 37 (18.97%) 0.899
 Cryoprecipitate(U) 30.46 (16.03) 26.53 (15.13) 0.003
 ALT (U/L) 131.08 (433.19) 72.26 (211.4) 0.069
 Pre-operative HM (n) 209 (38.28%) 91 (46.67%) 0.249
  1. AKI, acute kidney injury’; IBIL, indirect bilirubin; UO, urine output; GA, general anesthesia; PLT, platelets; LOS, length of stay; EBL, estimated blood loss; ALB, albumin; HE, hepatic encephalopathy; ALT, alanine transaminase; HM, hepatic malignancy