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Table 4 Absolute miRNA concentration measured by ddPCR in serum of the severely sarcopenic patients undergoing rehabilitation and healthy controls

From: Sarcopenia associates with SNAP-25 SNPs and a miRNAs profile which is modulated by structured rehabilitation treatment

 

Sarcopenic patients before rehabilitation

Sarcopenic patients after rehabilitation

Healthy controls

miR-93-5p (copies/ng)

183.00; 83.30–429.00#

617.00; 267.00–1320.00

117.00; 0.00–692.00^

miR-155-5p (copies/ng)

0.00; 0.00–121.00#

117.00; 100.00–292.00

53.30; 0.00–117.00^

miR-421-3p (copies/ng)

0.00; 0.00–175.00#

233.00; 158.00–454.00

66.7; 0.00–183.00#

miR-425-5p (copies/ng)

41.7; 17.10–97.90#

333.00; 104.00–1110.00

95.00; 0.00–433.00^

miR-451a (copies/ng)

5420.00; 2820.00–12,600.00^

12,233.00; 5154.17–30,041.67

983.00; 0.00–17,900.00*

miR-495-3p (copies/ng)

150.00; 0.00–271.00#

0.00; 0.00–150.00

150.00; 83.30–242.00^

miR-744-5p (copies/ng)

0.00; 0.00–187.00#

883.00; 0.00–1920.00

0.00; 0.00–92.52^

  1. Data are reported as median and interquartile range
  2. # p < 0.001 HC vs. sarcopenic patients after rehabilitation
  3. ^ p < 0.01 HC vs. sarcopenic patients after rehabilitation
  4. * p < 0.01 HC vs. sarcopenic patients before and after rehabilitation