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Table 2 Demographic and clinical characteristics of the severely sarcopenic patients who underwent rehabilitation and in whom circulatory miRNAs were analyzed and of the age-and-sex-matched non-sarcopenic healthy controls (HC)

From: Sarcopenia associates with SNAP-25 SNPs and a miRNAs profile which is modulated by structured rehabilitation treatment

  Sarcopenic patients Healthy controls
N 45 44
Gender (F:M) 37:8 32:12
Age, years 73.3 ± 8.3 71.9 ± 7.1
MMSE 27.8 ± 2.4 29.4 ± 0.5
SPPB pre-rehabilitation 0
0–1
11*
10–12
SPPB post-rehabilitation 2.2
1.2–3.0**
Right Handgrip pre-rehabilitation 19.4 ± 7.6
Right Handgrip post-rehabilitation 20.2 ± 7.8
Left Handgrip pre-rehabilitation 16.6 ± 6.6
Left Handgrip post-rehabilitation 16.1 ± 7.5
  1. Data for Age and MMSE are reported as mean ± standard deviation, median and Interquartile range are reported for SPPB values
  2. MMSE mini mental state evaluation, SPPB short physical performance battery
  3. * p = 0.002
  4. ** p < 0.0001 pre-vs. post-rehabilitation SPPB score