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Table 2 Demographic and clinical characteristics of the severely sarcopenic patients who underwent rehabilitation and in whom circulatory miRNAs were analyzed and of the age-and-sex-matched non-sarcopenic healthy controls (HC)

From: Sarcopenia associates with SNAP-25 SNPs and a miRNAs profile which is modulated by structured rehabilitation treatment

 

Sarcopenic patients

Healthy controls

N

45

44

Gender (F:M)

37:8

32:12

Age, years

73.3 ± 8.3

71.9 ± 7.1

MMSE

27.8 ± 2.4

29.4 ± 0.5

SPPB pre-rehabilitation

0

0–1

11*

10–12

SPPB post-rehabilitation

2.2

1.2–3.0**

–

Right Handgrip pre-rehabilitation

19.4 ± 7.6

–

Right Handgrip post-rehabilitation

20.2 ± 7.8

–

Left Handgrip pre-rehabilitation

16.6 ± 6.6

–

Left Handgrip post-rehabilitation

16.1 ± 7.5

–

  1. Data for Age and MMSE are reported as mean ± standard deviation, median and Interquartile range are reported for SPPB values
  2. MMSE mini mental state evaluation, SPPB short physical performance battery
  3. * p = 0.002
  4. ** p < 0.0001 pre-vs. post-rehabilitation SPPB score