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Table 4 Associations of CVD risk score trajectories with incident hard CVD (n = 2619)

From: Trajectories of cardiovascular disease risk and their association with the incidence of cardiovascular events over 18 years of follow-up: The Tehran Lipid and Glucose study

Events Events/ n
at risk (%)
Model 1* Model 2† Model 3‡
HR (95% CI) p-value HR (95% CI) p-value HR (95% CI) p-value
Low-Low 70/2004 (3.5) 1.00 (Reference) - 1.00 (Reference) 1.00 (Reference)
Medium-Medium 63/458 (13.8) 4.51 (3.21–6.34)  < 0.001 2.40 (1.46–3.97) 0.001 2.14 (1.19–3.85) 0.011
High-High 13/60 (21.7) 8.58 (4.74–15.53)  < 0.001 3.46 (1.56–7.70) 0.002 3.14 (1.15–8.52) 0.025
  1. CVD cardiovascular disease, HR hazard ratio, CI confidence interval
  2. *Unadjusted model
  3. Model 2 was adjusted for age at examination cycle four
  4. Model 3 was adjusted for age, education, and family history CVD at examination cycle four