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Table 4 Associations of CVD risk score trajectories with incident hard CVD (n = 2619)

From: Trajectories of cardiovascular disease risk and their association with the incidence of cardiovascular events over 18 years of follow-up: The Tehran Lipid and Glucose study

Events

Events/ n

at risk (%)

Model 1*

Model 2†

Model 3‡

HR (95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

Low-Low

70/2004 (3.5)

1.00 (Reference)

-

1.00 (Reference)

1.00 (Reference)

Medium-Medium

63/458 (13.8)

4.51 (3.21–6.34)

 < 0.001

2.40 (1.46–3.97)

0.001

2.14 (1.19–3.85)

0.011

High-High

13/60 (21.7)

8.58 (4.74–15.53)

 < 0.001

3.46 (1.56–7.70)

0.002

3.14 (1.15–8.52)

0.025

  1. CVD cardiovascular disease, HR hazard ratio, CI confidence interval
  2. *Unadjusted model
  3. Model 2 was adjusted for age at examination cycle four
  4. Model 3 was adjusted for age, education, and family history CVD at examination cycle four