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Table 1 Characteristics of NSCLC patients subjected to DNA-based NGS

From: Molecular characteristics and clinical outcomes of complex ALK rearrangements identified by next-generation sequencing in non-small cell lung cancers

Patient

Total no

ALK Gene fusions

P

Gender

 Male

3699

166 (4.5%)

0.002601

 Female

2877

177 (6.2%)

 

Age

 ≥ 60

3704

107 (2.9%)

< 0.001

 < 60

2872

236 (8.2%)

 

Histology

 Adenocarcinoma

4897

311 (6.4%)

< 0.001

 Squamous

982

7 (0.7%)

 

 Other*

697

25 (3.6%)

 

Sample type

 Surgical

1689

98 (5.8%)

0.3983

 Biopsy/cell block

4571

239 (5.2%)

 

 Liquid biopsy

316

6 (1.9%)

 
  1. *Other carcinomas included adenosquamous carcinoma (n = 76), large cell cancer (n = 17), large cell neuroendocrine carcinoma (n = 25), neuroendocrine carcinoma (n = 22), sarcomatoid carcinoma (n = 36), non-small cell lung cancer-not otherwise specified (n = 287) and unknown (n = 234)
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Journal of Translational Medicine

ISSN: 1479-5876

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