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Table 2 Baseline characteristics of m. vastus lateralis for COPD and Healthy

From: Chronic obstructive pulmonary disease does not impair responses to resistance training

  COPD Healthy Sex-adjusted estimated difference
COPD – Healthy (95% CI) P-value
Cross-sectional area (µm2)
 Type I 4614 (1088) 3720 (951) 449 (70, 827) 0.020*
 Type II 3639 (1235) 3059 (1121) 182 (− 118, 482) 0.232
Myonuclei per fiber
 Type I 2.2 (0.9) 2.1 (0.9) − 0.1 (− 0.4, 0.2) 0.357
 Type II 2.1 (0.7) 1.9 (0.7) − 0.1 (− 0.3, 0.2) 0.504
Myonuclear domain (cross sectional area/nuclei per fiber)
 Type I 2292 (585) 1928 (1030) 360 (107, 613) 0.006*
 Type II 1775 (529) 1740 (1049) − 62 (− 316, 191) 0.628
Fiber type proportion (%)
 Type I 52 (15) 65 (14) − 16 (− 24, − 9)  < 0.001*
 Type IIA 32 (12) 23 (11) 10 (4, 16) 0.001*
 Type IIX 13 (7) 9 (6) 5 (1, 9) 0.007*
 Type IIA/IIX 3 (2) 2 (2) 0.7 (− 0.4, 1.9) 0.159
Total RNA (ng / ml) 477 (103) 504 (106) − 20 (-59, 18) 0.302
  1. COPD, participants diagnosed with chronic obstructive pulmonary disease; Healthy, healthy control participants. Data presented as mean (SD), and sex-adjusted estimated mean differences between study clusters (95% CI). Alpha level at p < 0.05