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Table 2 Areas of significant decrease and increase in BOLD response in patients and controls during implicit cognitive reappraisal (NNEG-DESC versus NEG-DESC)

From: Neural basis of implicit cognitive reappraisal in panic disorder: an event-related fMRI study

 

Brain regions

BA

Side

Cluster size

MNI coordinates

T-value

(voxels)

x

y

z

 

PD group: NNEG-DESC > NEG-DESC

Precentral Gyrus/Postcentral Gyrus

4/6

L

1876

− 40

− 20

58

6.04

Cerebellum

–

R

691

18

− 86

− 40

4.63

HC group: NNEG-DESC > NEG-DESC

Postcentral Gyrus/Precentral Gyrus/Inferior Parietal Loule

3/7/40

R

1371

47

− 29

58

− 5.92

Dorsolateral prefrontal cortex/Dorsomedial prefrontal cortex

6/8/9

L

771

− 43

20

41

5.8

Lateral Orbitofrontal Cortex

10/11

L

523

− 40

43

− 22

4.56

Cerebellum

–

R

432

15

− 80

− 37

5.21

Angular Gyrus/Precuneus/Inferior Parietal Lobule

19/39

R

409

40

− 74

48

4.90

Middle Temporal Gyrus/Inferior Temporal Gyrus

20/21

R

399

62

− 44

− 13

4.34

Postcentral Gyrus/Precuneus/Superior parietal lobule

7

R

366

37

55

− 23

4.81

Angular Gyrus/Middle Temporal Gyrus/Precuneus

19/39

L

271

− 40

− 65

44

4.64

Interaction effects: HC(NNEG-DESC > NEG-DESC) > PD (NNEG-DESC > NEG-DESC)

Postcentral Gyrus/precuneus/Superior parietal lobule

7

R

295

20

− 51

66

4.33

Dorsolateral prefrontal cortex ext

6/9

R

230

11

27

60

− 3.82

Dorsomedial prefrontal cortex

8

R

 

9

19

51

− 3.22

  1. PD panic disorder, HC healthy control, ext extending into, BA Brodmann area, L left, R right
  2. x y z = MNI coordinates of the peak active voxel