Table 4 The diagnostic accuracy of WT1 mRNA and 1/ACE mRNA for predicting incipient DN
From: WT1 and ACE mRNAs of blood extracellular vesicle as biomarkers of diabetic nephropathy
Parameters | Threshold values | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | AUC (95% CI) | p value |
|---|---|---|---|---|---|---|---|
WT1 mRNA | 1.50 | 50.0 | 74.0 | 55.9 | 69.1 | 0.63 (0.55, 0.72) | 0.003 |
\(\frac{1}{{{\text{ACE}}\;{\text{mRNA}}}}\) | 1.15 | 65.2 | 61.0 | 52.4 | 72.6 | 0.62 (0.54, 0.71) | 0.005 |