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Table 2 Correlations of WT1 mRNA and ACE mRNA with demographic and clinical parameters within total sample, DN group and DM group, separately

From: WT1 and ACE mRNAs of blood extracellular vesicle as biomarkers of diabetic nephropathy

 

mRNA

Age

BMI

FBS

HbA1c

Urea

S. Cr

eGFR

Alb/Cr

Total

WT1

r

0.222

− 0.167

0.423

0.571

0.193

0.200

0.042

0.509

p

0.004

0.252

< 0.001

 < 0.001

0.002

0.001

0.636

< 0.001

ACE

r

− 0.101

0.180

− 0.402

− 0.592

− 0.135

− 0.177

0.058

− 0.465

p

0.190

0.216

< 0.001

< 0.001

0.032

0.005

0.505

< 0.001

DN group

WT1

r

0.161

− 0.207

0.270

0.341

0.020

0.221

− 0.201

0.602

p

0.239

0.565

0.006

< 0.001

0.845

0.025

0.326

< 0.001

ACE

r

− 0.110

0.250

− 0.340

− 0.445

− 0.021

− 0.159

0.273

− 0.474

p

0.424

0.486

0.001

< 0.001

0.836

0.110

0.177

< 0.001

DM group

WT1

r

0.040

− 0.172

0.280

0.518

0.001

0.007

0.138

0.018

p

0.736

0.331

0.005

< 0.001

0.991

0.944

0.262

0.864

ACE

r

0.050

0.154

− 0.372

− 0.685

0.064

− 0.025

0.040

− 0.234

p

0.670

0.386

< 0.001

< 0.001

0.526

0.803

0.747

0.020

  1. BMI body mass index, FBS fasting blood glucose, S. Cr serum creatinine, eGFR estimated glomerular filtration rate, Alb/Cr urine albumin/creatinine ratio
  2. r = correlation coefficient of spearman, p = p-value