Fig. 5

DEGs in global and local networks. a From the inside out: expression average (pre-treatment NR higher 3–0, pre-treatment R higher 0–1, on-treatment NR higher 1.5–0, and on-treatment R higher 0–1) and p-values (0.05–0) of DEGs. Gene sets function enrichment. on-treatment and pre-treatment DEGs. b and c SIRPA and CD14 expression in melanoma immunity single cells. d DEGs in 11 networks within cell clusters