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Table 5 Associations and strengths of the presence of BME and structural damage on MRI-SIJs in HLA-B27( +) and HLA-B27(−) nr-axSpA subjects, respectively (Pearson Chi-Square & phi scores)

From: MRI contributes to accurate and early diagnosis of non-radiographic HLA-B27 negative axial spondyloarthritis

Structural damage

BME ( +) vs. BME (–)

p value

phi scores

HLA-B27( +)

n = 42

 Sclerosis ( +)

65.4% vs. 34.6%

0.001**

0.503

 Erosion ( +)

100% vs. 0%

NA

NA

 fJSW ( +)

75% vs. 25%

0.018*

0.370

 DPa

57.1% vs. 42.9%

0.318

0.156

 TPb

75% vs. 25%

0.018*

0.370

 Abnormal serum CRP

35.7% vs. 64.3%

0.429

0.100

 Abnormal serum ESR

63.6% vs. 36.4%

0.179

0.210

HLA-B27(–)

n = 61

 Sclerosis ( +)

32.4% vs. 67.6%

0.337

0.122

 Erosion ( +)

27.6% vs. 72.4%

0.911

0.014

 fJSW ( +)

63.6% vs. 36.4%

0.003**

0.377

 DPa

22.7% vs. 77.3%

0.539

− 0.078

 TPb

60% vs. 40%

0.012*

0.320

 Abnormal serum CRP

54.5% vs. 45.5%

0.524

0.100

 Abnormal serum ESR

31.3% vs. 68.7%

0.690

0.051

  1. BME bone marrow edema, MRI magnetic resonance imaging, SIJ sacroiliac joint, nr-axSpA nonradiographic spondyloarthritis, fJSW focal joint space widening, CRP C reactive protein, ESR erythrocyte sedimentation rate, NA not applicable
  2. aDP, double positive, dual presence of sclerosis and erosion on MRI-SIJs;
  3. bTP, triple positive, simultaneous presence of sclerosis, erosion, and fJSW on SIJ MRI
  4. *p value < 0.05
  5. **p value < 0.01; phi scores were used for association measure between binary variables