Fig. 1
From: SRPK1/AKT axis promotes oxaliplatin-induced anti-apoptosis via NF-κB activation in colon cancer
SRPK1 is overexpressed and associated with clinical stage, TNM classification, and prognosis of survival in patients with colon cancer. a SRPK1 mRNA expression analysis in TCGA pan-cancer samples. b SRPK1 mRNA expression analysis in TCGA colon cancer samples and normal tissues. c SRPK1 protein level analysis in CPTAC pan-cancer samples. d SRPK1 protein level analysis in CPTAC colon cancer samples and normal tissues. e The level of SRPK1 in colon cancer cell lines. f The level of SRPK1 in colon cancer patients’ tissues and normal tissues. g IHC analysis of SRPK1 in the tissues of patients with colon cancer. h A statistical analysis of the average MOD of SRPK1 staining (n = 10). i SRPK1 high (n = 97)/low (n = 51) expression is significantly associated with clinical stage and TNM classification of paraffin embedded sections from patients with colon cancer. j The correlation of SRPK1 levels and overall survival. **p < 0.01. SRPK1 Serine-arginine protein kinase 1, TCGA The Cancer Genome Atlas, CPTAC Clinical Proteomic Tumor Analysis Consortium, IHC immunohistochemistry, MOD mean of optical density, TNM tumor-mode-metastasis