Fig. 2

The different immune profiles between the two molecular subtypes. a Discrepancies of immune cell infiltration and expression of immune-related pathways between cluster-A and cluster-B. b–e Distributions of immune score, stromal score, EATIMATE score, and tumor purity between cluster-A and cluster-B. The distance of both ends of boxes represents the interquartile range of values and the thick line represents the median value. The significance of the Mann–Whitney test is shown by an asterisk (*P < 0.05; **P < 0.01; ***P < 0.001). f Expression variation in gene signatures for dysfunctional T cell states and TGF beta-encoding genes between subtypes