Table 2 Demographics of SCD patients with HBSE genotype compared to classic SCD [46]
From: Manifestations of HbSE sickle cell disease: a systematic review
Characteristics | HBSE reported cases, N = 68 |
|---|---|
Agea (years) | Mean: 20.9 ± 18.26 years |
HbS (percentage) | Mean: 61.1 ± 7.25 |
HbE (percentage) | Mean: 32.3 ± 5.06 |
HbF (percentage) | Mean: 2.2 ± 2.16 |
Hemoglobin (g/dl) | Mean: 11.64 g/dl ± 1.73 |
Mean (males): 11.69 | |
Mean (females): 11.61 | |
MCV (fl) | Mean: 70.5 ± 6.01 |
Presentation (diagnosis) | Asymptomatic at presentation: 31 (45%) |
Presentation at birth: 2 (2.8%) | |
Discovered in Clinic: 1 (1.4%) | |
Diagnosed during hospitalization: 8 (11.8%) | |
Discovered Postmortem: 2 (2.8%) | |
Asymptomatic cases (no complications found) | N: 35 (51.5%) |
Treatments given | Transfusion (exchange or simple): 7 (10.2%) Hydroxyurea: 3 (4.4%) |
Death due to complications | N: 3 (4.2%) |