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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Droplet digital PCR allows vector copy number assessment and monitoring of experimental CAR T cells in murine xenograft models or approved CD19 CAR T cell-treated patients

Fig. 5

Long-term monitoring and follow-up of CAR T cells in treated DLBCL or B-ALL patients. Ten patients (DLBCL) receiving axi-cel and 7 (4 B-ALL and 3 DLBCL) receiving tisa-cel were monitored using 28BBz or 28z ddPCR (blue lines, left Y-axis) on gDNA extracted from circulating PB cells. CD19 CAR T cell numeration (red lines, right Y-axis), obtained by FC, is plotted (green lines, right Y-axis) on the same respective graph. AUC: area under the curve day 0 to 28, calculated with GraphPad software. (*) highlights patients in whom CD19+ cells reappear

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Journal of Translational Medicine

ISSN: 1479-5876

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