Fig. 1

A The scale independence (the left plot) and mean connectivity (the right plot) corresponding to different soft-thresholding values. B The cluster dendrogram (the upper part) and the co-expression modules (the lower part) generated by average linkage hierarchical clustering method. the branches of the dendrogram represent individual genes. The height indicates the Euclidean distance. Each module that contains weighted co-expressed genes, is displayed with a distinct color. C The heatmap of topological overlap using 400 randomly selected genes. The genes are divided into different colors (modules), shown under the cluster dendrogram. D The heatmap of module eigengene adjacency, which stands for the relationship between distinct co-expression modules. E The module-trait relationship plotter. All modules (colors) are displayed on the longitudinal axis, while all prognostic markers are displayed on the transverse axis. Each cell contains R² and p value of correlations between the modules and prognostic markers by Spearman’s method. The gradient color of each cell corresponds to the R² (red = 1, blue =  − 1). F The module-trait relationships for the combos of NPM1 and FLT3-ITD status