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Table 2 Results from CSA, HRR and HRR normalized to CSA

From: The effect of revascularization on recovery of mitochondrial respiration in peripheral artery disease: a case control study

  Chronic ischemic muscle (gastrocnemius muscle) Non-ischemic muscle (lateral vastus muscle)
  Preoperative Postoperative p-value Preoperative Postoperative p-value
CSA (nmol/min/mg protein)     
  281.4 (252.4–391.8) 438.5 (361.4–471.3) 0.010 310.6 (266.8–357.4) 317.6 (278.3–324.1) 0.940
Mitochondrial respiration [pmol/(s*mg)]   
 MOctL 16.1 (13.7–18.4) 13.7 (12.2–16.1) 0.575 16.5 (14.1–19.4) 18.3 (16.3–19.9) 0.169
 MOctP 24.4 (20.9–29.7) 20.7 (17.5–22.5) 0.286 26.7 (23.4–29.4) 29.2 (23.3–33.7) 0.205
 P 66.6 (57.8 –78.3) 53.2 (49.8–52.1) 0.006 64.2 (54.2–67.4) 60.2 (54.3–73.2) 0.341
 E 75.9 (59.0–85.1) 59.1 (46.7–64.8) 0.002 69.5 (59.5–75.8) 65.7 (55.7–76.0) 0.617
Mitochondrial respiration [pmol/(s*mg)] per CSA   
 MOctL 0.048 (0.040–0.074) 0.036 (0.031–0.040) 0.156 0.049 (0.048–0.053) 0.059 (0.049–0.078) 0.176
 MOctP 0.072 (0.060–0.120) 0.051 (0.040–0.063 0.169 0.079 (0.078–0.083) 0.094 (0.079–0.110) 0.326
 P 0.218 (0.196–0.266) 0.132 (0.166–0.150) 0.007 0.185 (0.173–0.230) 0.213 (0.171–0.266) 0.537
 E 0.230 (0.195–0.279) 0.129 (0.120–0.154) 0.005 0.211 (0.180–0.252) 0.196 (0.176–0.243) 0.940
  1. Results from CSA, HRR and HRR normalized to CSA; Data are expressed as median with IQR in brackets; A p-value < 0.05 is considered to be significant; CSA Citrate synthase activity, MOctL maximal respiration after titration of malate and octanoyl, MOctP maximal respiration after addition of ADP, P maximal respiration after addition of pyruvate and succinate, E maximal respiration after addition of FCCP