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Table 3 The mRNA expression of thioredoxin reductase-1 (TrxR1), thioredoxin (Trx), glutathione peroxidase 7 (GPX7), oxidation resistance 1 (OXR1), catalase (CAT) and superoxide dismutase 2 (SOD2) in regulatory T (Treg) cells and corresponding conventional T (Tconv) cells from CCS patients and controls

From: Oxidative stress response in regulatory and conventional T cells: a comparison between patients with chronic coronary syndrome and healthy subjects

 

CCS patients (n = 10)

Controls (n = 10)

 

Gene

Treg cells

P

TrxR1

3.7 (2.6–4.4)

3.0 (2.6–3.9)

0.973

Trx

7.9 (4.6–10)

6.2 (4.0–6.7)

0.445

GPX7

2.0 (1.2–2.2)

1.6 (1.3–2.4)

0.621

OXR1

2.9 (1.8–3.3)

2.5 (1.7–2.7)

0.681

CAT

3.6 (2.4–4.0)

3.1 (2.8–3.9)

0.929

SOD2

1.9 (1.1–2.0)

1.7 (1.2–2.1)

0.949

 

Tconv cells

 

TrxR1

1.7 (1.4–2.0)

1.4 (1.0–1.6)

0.033

Trx

2.8 (2.2–3.2)

1.9 (1.5–2.4)

0.104

GPX7

1.4 (1.4–2.1)

1.5 (1.4–1.7)

0.267

OXR1

1.8 (1.4–1.9)

1.7 (1.4–1.9)

0.601

CAT

2.4 (1.9–2.7)

1.7 (1.4–2.8)

0.204

SOD2

1.6 (1.4–2.1)

1.3 (0.8–1.5)

0.091

  1. Values are given as median (interquartile range). CCS, chronic coronary syndrome, Bolded P-value represents statistical significance