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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Oxidative stress response in regulatory and conventional T cells: a comparison between patients with chronic coronary syndrome and healthy subjects

Fig. 2

The expression of oxidative stress-associated genes in Treg and Tconv cells from 20 study subjects (10 CCS patients and 10 controls). A Genes with significant differences between patients and controls included catalase (CAT), oxidation resistance 1 (OXR1), thioredoxin reductase-1 (TrxR1) and thioredoxin (Trx). B Genes with non-significant differences included glutathione peroxidase 7 (GPX7) and superoxide dismutase 2 (SOD2). Graphs depict arbitrary values normalized against internal control and 18S rRNA in each individual sample. C Thioredoxin reductase 1 (TrxR1) (ng/mL) levels in cell supernatants of Treg and Tconv cells treated with either 0 or 30 µM H2O2. Number of study subjects per dose of H2O2 were n = 32 for 0 µM and n = 32 for 30 µM. In all figures, box plots and bars display median and i-q range values’

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