Fig. 8

Box-scatter plots for the 15 hubgenes expression in GC from TCGA and the effect of circRNAs overexpressions on hubgenes expressions. A–O Box scatter plots for the expression of 15 hubgenes in GC from TCGA: A ATF3, B BTG2, C DUSP1, D EGR1, E FGF2, F FOSB, G GNAI1, H GNAO1, I GNAZ, J GNG7, K ITPKB, L ITPR1, M JUND, N NR4A3, and OPRKCB. P–Q Overexpressing plasmids of the six circRNAs were constructed and GC cells were transfected with pooled circRNA vectors. P The overexpression efficiency of circRNA vectors on RNA level of circRNAs were measured by qRT-PCR analysis. Q The mRNA levels of 15 hubgenes in GC cells transfected with circRNA vectors by qRT-PCR analysis