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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Identification of immune subtypes of cervical squamous cell carcinoma predicting prognosis and immunotherapy responses

Fig. 2

Identification of cervical SCC subtypes with distinct outcomes using NMF consensus clustering. A Estimation of the factorization rank (2 to 6; x-axis) using cophenetic, dispersion, and silhouette coefficients (y-axis). There is a large decrease in the stability between rank 2 and 3, indicating that rank 2 has the optimal robustness. B PCA analysis of two subtypes from the SCCH cohort. Kaplan–Meier curves for C overall survival (OS) and D progression-free survival (PFS) show the distinct outcome between subtype 1 and subtype 2 in the validation set. E PCA plots of two subtypes in the TCGA cohort. Kaplan–Meier curves for F OS and G PFS show the distinct outcome between subtype 1 and subtype 2 in the TCGA cohort. H PCA plots of two subtypes in the GEO cohort. I Survival analysis of the different subtypes in the GEO cohort. The statistical significance of prognosis was determined by a log-rank test

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