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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: miR-20a suppresses Treg differentiation by targeting Map3k9 in experimental autoimmune encephalomyelitis

Fig. 5

The expression of Map3k9 is influenced by miR-20a. A The mRNA expression level of Map3k9 in CD4+ T cells from EAE and control mice. B The mRNA expression level of Map3k9 in spinal cord tissues from EAE and control mice. C, D. The protein expression level of Map3k9 in spinal cord tissues from EAE and control mice tested by western blot. E Linear regression analysis of the correlation between the expression of miR-20a and Map3k9 in CD4+ T cells from EAE and control mice. F Linear regression analysis of the correlation between the expression of miR-20a and Map3k9 in spinal cord tissues from EAE and control mice. G The mRNA level of Map3k9 in the peripheral blood leucocytes of MOG antibody-associated demyelinating patients and HCs. Data are shown as mean ± SEM. ** p < 0.01, *** p < 0.001 using unpaired Student’s t-test

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