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Table 5 Pleiotropy analysis of 11 selected plasma vitamin C genetic variants

From: Effect of plasma vitamin C levels on Parkinson’s disease and age at onset: a Mendelian randomization study

GWAS dataset

MR-Egger intercept

MR-PRESSO

Heterogeneity test

intercept

95% CI

P value

P value

I2 (%)

95% CI

Q P value

PD

− 0.016

[− 0.043, 0.011]

0.243

0.08

42.4

[0.0%; 71.5%]

0.0669

PD AAO

0.127

[− 0.011, 0.266]

0.072

0.271

15.6

[0.0%; 56.1%]

0.2951

  1. The significance threshold is P < 0.05