Fig. 7
From: Interleukin-24 regulates mucosal remodeling in inflammatory bowel diseases
Tissue remodeling-associated factors in WT vs. Il20rb KO mice after DSS treatment. Relative protein level of FN1 (c, d) and αSMA (c, e) in colon tissue were measured by Western blot analysis, relative mRNA expression of Tgfb1 (a), Pdgfb (b), Col1a1 (e), Col3a1 (f), Fn1 (g), Acta2 (h), Mmp2 (i), Mmp9 (j), Timp1 (k) and Timp2 (l) was measured by real-time PCR, by comparison with Gapdh as internal control (n = 6). Results are presented as mean ± SD. *p < 0.05 vs. WT control; #p < 0.05 vs. WT DSS (Mann–Whitney U-test)