Fig. 2

ABE treatment enhances osteogenesis and reverses bone marrow adipogenesis. a Histological features of normal bone from a normal rat, and osteonecrotic bone from rats with steroid-induced ONFH with or without ABE treatment. b Statistical analysis of the differences of the ratio of empty lacuna, adipose tissue area, and adipocyte perimeter in the control, model, ABE 10 g/kg, ABE 15 g/kg, and ABE 22.5 g/kg groups. Data are presented as the mean ± S.D. (n = 20 for control, n = 25 for model group, n = 20 for ABE treatment groups). ##: P < 0.01, in comparison with the control group. * and **: P < 0.05 and P < 0.01, respectively, in comparison with the model group. The arrow heads indicate necrosis area