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Table 1 Identified exosomal cargoes of stem cells that improve ischemic diseases

From: Application of stem cell-derived exosomes in ischemic diseases: opportunity and limitations

Exosomes from Stem cells Cargo Disease
Cardiosphere-derived cells miRNA-210, miRNA-130a, miRNA-126
miRNA-146a
Myocardial ischemia
CD34+ cell Hedgehog proteins Myocardial ischemia
Embryonic Stem Cells Not known Myocardial ischemia
Induced Pluripotent Stem Cells Not known Myocardial ischemia
Mesenchymal Stem Cells CXCR4, miRNA-21, EMMPRIN Myocardial ischemia
Stem cells derived from adipose tissue miRNA-125a Chronic wound healing
Mesenchymal Stem Cells miRNA-21-3p, miRNA-126, VEGF Chronic wound healing
CD34 +  miRNA-126-3p Chronic wound healing
Stem cells derived from adipose tissue IL-6 Chronic wound healing
Stem cells derived from adipose tissue miRNA-181b-5p Stroke
Mesenchymal Stem Cells Not known Stroke
Mesenchymal Stem Cells VEGF protein, miRNA-210-3p, Peripheral arterial disease
CD34 + cells miRNA-126-3p Peripheral arterial disease