Table 1 Identified exosomal cargoes of stem cells that improve ischemic diseases
From: Application of stem cell-derived exosomes in ischemic diseases: opportunity and limitations
Exosomes from Stem cells | Cargo | Disease |
|---|---|---|
Cardiosphere-derived cells | miRNA-210, miRNA-130a, miRNA-126 miRNA-146a | Myocardial ischemia |
CD34+ cell | Hedgehog proteins | Myocardial ischemia |
Embryonic Stem Cells | Not known | Myocardial ischemia |
Induced Pluripotent Stem Cells | Not known | Myocardial ischemia |
Mesenchymal Stem Cells | CXCR4, miRNA-21, EMMPRIN | Myocardial ischemia |
Stem cells derived from adipose tissue | miRNA-125a | Chronic wound healing |
Mesenchymal Stem Cells | miRNA-21-3p, miRNA-126, VEGF | Chronic wound healing |
CD34 +  | miRNA-126-3p | Chronic wound healing |
Stem cells derived from adipose tissue | IL-6 | Chronic wound healing |
Stem cells derived from adipose tissue | miRNA-181b-5p | Stroke |
Mesenchymal Stem Cells | Not known | Stroke |
Mesenchymal Stem Cells | VEGF protein, miRNA-210-3p, | Peripheral arterial disease |
CD34 + cells | miRNA-126-3p | Peripheral arterial disease |