Fig. 1From: Seasonal rhythms of vasopressin release and aquaporin-2 excretion assure appropriate water conservation in humansComparison of baseline plasma AVP in the cold and warm seasons expressed as pg/ml. Plasma vasopressin was determined using a competitive RIA kit (Vasopressin; Nichols Institute Diagnostics, San Juan Capistrano, CA, USA). a AVP was significantly higher in the warm season (April–October) as compared with the cold season (November-March) in all participants, ****p < 0.0001, n = 52. b In males, AVP was significantly higher in the warm season respect to the cold season, ****p < 0.0001, n = 24. c Similarly, in females, AVP was significantly higher in the warm season with respect to the cold season ****p < 0.0001, n = 28. Values are expressed as means ± SEM. Student’s t-test was used for the statistical analysisBack to article page