Skip to main content
Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer

Fig. 2

a Frequency of somatic PIK3CA and ERBB-family mutations in HER2-positive (n = 29) and HER2-negative (n = 40) tumour samples identified using the Agena MassArray system and b (i) Progression free survival (PFS) and (ii) overall survival (OS) in HER2-positive gastric cancer patients with and without PIK3CA and/or ERBB-family mutations; (iii) PFS and (iv) OS in HER2-negative gastric cancer patients with and without PIK3CA and/or ERBB-family gene mutations; (v) PFS and (vi) OS in HER2-positive and HER2-negative gastric cancer patients with PIK3CA and/or ERBB-family gene mutations. p-values were calculated using the log rank (Mantel–Cox) test with GraphPad Prism

Back to article page