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Table 2 Association of the marker change (zonulin, calprotecin) with taxon/pathway change—a linear mixed model

From: The gut microbiota is associated with the small intestinal paracellular permeability and the development of the immune system in healthy children during the first two years of life

Taxon/Pathway vs marker (changes)

Common slope (no interaction)

Interaction (taxon/pathway change x time interval)

β (SE)

P

Q

P

Q

Ruminococcus (torques group) vs calprotectin

2.94 (0.81)

0.002

0.015

0.424

0.910

CENTFERM-PWY vs calprotectin

− 4.54 (1.08)

0.0002

0.028

0.412

0.993

PWY-6590 vs calprotectin

− 4.48 (1.16)

0.0002

0.026

0.421

0.993

PENTOSE-P-PWY vs zonulin

9.49 (1.93)

3.98e−6

0.001

0.123

0.356

PWY-6545 vs zonulin

Na

4.15e-5

0.014

PWY-6901vs zonulin

Na

0.0005

0.046

PWY0-845 vs zonulin

Na

0.0008

0.049

  1. β, coefficient estimate; SE, standard error; Q -FDR adjusted P value, Na, not applicable