Fig. 4

Weighted gene co-expression network analysis (WGCNA). a Clustering dendrogram of 55 samples. Sample clustering revealed that that sample GSM1620246 required removal from subsequent analysis due to outliers. b, c Soft-threshold power for WGCNA. d Dendrogram of all expressed genes in the top 25% of variance clustered based on a dissimilarity measure (1 − TOM). e Heatmap of correlation between ME and EPN-PF modules. f A scatterplot of Gene Significance (GS) for group vs. Module Membership (MM) in the blue module. There is a highly significant correlation between GS and MM in this module. 180 hub genes were selected in the blue module