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Table 1 Baseline clinical characteristics of enrolled dilated cardiomyopathy cases

From: Genetic analysis using targeted next-generation sequencing of sporadic Chinese patients with idiopathic dilated cardiomyopathy

Characteristics

(n = 24)

Age at onset, years

39.8 ± 12.3

Female gender, n (%)

5 (21%)

Hypertension, n (%)

6 (25%)

Diabetes mellitus, n (%)

2 (8%)

Smoking

6 (25%)

Alcohol

4 (17%)

Cholesterol, mmol/L

4.7 ± 1.6

LDL-c, mmol/L

3.2 ± 1.1

NT-proBNP, pg/mL

2057.5 (698,18,381)

NYHA III or IV, n(%)

21 (87.5%)

ICD, n (%)

2 (8%)

Atrial fibrillation

2 (8%)

Complete RBBB/LBBB

1 (4%)

LVEF, %

27.0 ± 9.9

LVEDD, mm

70.1 ± 7.8

LA diameter, mm

49.4 ± 9.6

ACEI/ARB/ARNI, n (%)

18 (75%)

Beta-blockers, n (%)

21 (87.5%)

Spironolactone, n (%)

22 (91.7%)

Diuretics, n (%)

21 (87.5%)

  1. All variables are given as either number present (% of total number) or mean ± SD, except for NT-proBNP (N-terminal B-type natriuretic peptide), which is given as mean and range
  2. NYHA, New York Heart Association functional classification; ICD, implantable cardioverter defibrillator; RBBB/LBBB, right bundle branch block/left bundle branch block; LVEDD, left ventricular end-diastolic dimension; LA, left atrium; ACEI/ARB/ARNI, angiotensin converting enzyme inhibitor/angiotensin receptor blocker/angiotensin receptor-neprilysin inhibitor