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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Inhibition of DKC1 induces telomere-related senescence and apoptosis in lung adenocarcinoma

Fig. 1

High expression of DKC1 in LUAD predicts poor prognosis. a The mRNA levels of DKC1 in 83 LUAD tissues and paired adjacent normal tissues from the GEO database (GSE75037). b The mRNA levels of DKC1 in LUAD and adjacent normal tissues from the TCGA database. c Kaplan–Meier analysis of overall survival (OS) of LUAD patients according to DKC1 level from the TCGA LUAD database. d, e Immunohistochemistry (IHC) analysis of DKC1 expression in LUAD tissue microarray. d Representative IHC staining of DKC1 in the adjacent normal lung tissues, LUAD tissues with low or high DKC1 expression. Scale bar: 200 µm. e Kaplan–Meier analysis of OS in LUAD patients according to the DKC1 expression. f, g Correlation analysis between the DKC1 level and the TERC abundance or the TERT abundance in the TCGA LUAD database. **P < 0.01, ***P < 0.001

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