Fig. 4

LDHA inhibition alters cell cycle distribution after irradiation. A549 and H1975 cells were pretreated with or without 20 mM oxamate and irradiated with 6 Gy X-ray, after 24 h incubation, flow cytometry was performed to detect alternations in cell cycle distribution. a, b A549 cells; c, d H1975 cells. Con control, Oxa oxamate, IR irradiation. Error bars represent ± SD of N = 3 experiments, *p < 0.05, compared to the control group; ^#p < 0.05, compared to the irradiation group