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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Targeting lactate dehydrogenase a improves radiotherapy efficacy in non-small cell lung cancer: from bedside to bench

Fig. 3

LDHA inhibition by oxamate enhanced the radiosensitivity of A549 and H1975 cells in vitro. a Cells pretreated with 20 mM oxamate or negative control were incubated for 48 h and then subjected to a range doses of irradiation (0, 0.5, 1, 3, 6, 9 Gy). Two weeks later, colonies with ≥ 50 cells were counted. b, c Survival curves were calculated using a multitarget single-hit model. Data represent three independent experiments. Con control, Oxa oxamate, IR irradiation

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