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Table 4 Distribution of the degree of deconditioning according Parsaik and colleagues across ME/CFS hemodynamic groups (normal HR/BP response, POTS, and dOH), all with a significant CBF decrease as measured during HUT

From: Deconditioning does not explain orthostatic intolerance in ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome)

Degree deconditioning* NormHRBP (n = 105)(%) POTS (n = 39) (%) dOH (n = 27) (%) Total
No deconditioning: %peak VO2 ≥ 85% (n =) 27 (26%) 4 (11%) 7 (26%) 38
Mild deconditioning %peak VO2 65–85% (n =) 33 (31%) 13 (33%) 7 (26%) 53
Severe deconditioning: %peak VO2 < 65%(n =) 45 (43%) 22 (56%) 13 (48%) 80
Total 105 39 27 171
  1. Chi square statistics = 5.41(p = 0.25)(3 × 3 table)
  2. dOH delayed orthostatic hypotension during HUT, NormHRBP normal heart rate and blood pressure response during HUT, POTS postural orthostatic tachycardia syndrome during HUT, %peak VO2 oxygen consumption as percentage of normal values of a population study [19]
  3. * Subgrouping of the degree of deconditioning according to Parsaik et al. [6]