Table 3 Hemodynamic data during HUT in ME/CFS patients with a normal HRBP response (group 1), with POTS (group 2) and with dOH (group 3), all with a significant CBF decrease as measured during HUT
HUT data | Group 1 NormHRBP (n = 105) | Group 2 POTS (n = 39) | Group 3 dOH (n = 27) | Ordinary one-way ANOVA with post hoc Tukey’s test |
|---|---|---|---|---|
HR supine (bpm) | 73 (11) | 77 (14) | 73 (10) | F (2, 168) = 1.83; p = 0.16 |
HR end tilt (bpm) | 90 (14) | 114 (24) | 90 (16) | F (2, 168) = 29.52; p < 0.0001; 1vs2 p < 0.0001; 1vs3 p = 0.99; 2vs3 p < 0.0001 |
SBP supine (mmHg) | 134 (15) | 132 (16) | 142 (19) | F (2, 168) = 3.14; p = 0.04# |
SBP end tilt (mmHg) | 131 (16) | 119 (24) | 109 (16) | F (2, 168) = 19.14; p < 0.0001; 1vs2 p = 0.0008; 1vs3 p < 0.0001; 2vs3 p = 0.09 |
DBP supine (mmHg) | 79 (8) | 78 (8) | 81 (9) | F (2, 168) = 1.21; p = 0.30 |
DBP end tilt (mmHg) | 84 (9) | 81 (16) | 72 (13) | F (2, 168) = 10.91; p < 0.0001; 1vs2 p = 0.25; 1vs3 p < 0.0001; 2vs3 p = 0.01# |
CBF supine (ml/min) | 628 (107) | 608 (96) | 611 (98) | F (2, 168) = 0.70; p = 0.50 |
CBF end tilt (ml/min) | 456 (83) | 435 (79) | 435 (79) | F (2, 168) = 1.29; p = 0.28 |
%CBF reduction | − 27.4 (6.1) | − 28.6 (5.3) | − 28.8 (4.9) | F (2, 168) = 0.98; p = 0.38 |