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Table 2 CPET data in ME/CFS patients with a normal HR/BP response (group 1), ME/CFS patients with POTS (group 2), and ME/CFS patients with dOH (group 3), all with a significant CBF decrease as measured during HUT

From: Deconditioning does not explain orthostatic intolerance in ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome)

CPET data Group 1
NormHRBP (n = 105)
Group 2
POTS (n = 39)
Group 3
dOH (n = 27)
Ordinary one-way ANOVA with post hoc Tukey’s test
HR rest (bpm) 86 (14) 86 (12) 86 (15) F (2, 168) = 0.02; p = 0.98
HR peak (bpm) 147 (23) 146 (19) 146 (25) F (2, 168) = 0.03; p = 0.97
SBP rest (mmHg) 125 (16) 120 (14) 128 (15) F (2, 168) = 1.25; p = 0.29
DBP rest (mmHg) 84 (10) 81 (11) 83 (12) F (2, 168) = 0.67; p = 0.52
SBP peak (mmHg) 165 (26) 158 (26) 161 (26) F (2, 168) = 0.79; p = 0.46
DBP peak (mmHg) 99 (13) 92 (13) 96 (12) F (2, 168) = 2.36; p = 0.10
VT VO2 (ml/min/kg) 12 (4) 11 (3) 12 (4) F (2, 168) = 1.28; p = 0.28
Peak VO2 (ml/min/kg) 21 (7) 19 (5) 21 (7) F (2, 168) = 0.80; p = 0.45
%VT VO2 41 (11) 36 (11) 41 (12) F (2, 168) = 2.81; p = 0.06
%peak VO2 70 (21) 62 (16) 71 (21) F (2, 168) = 2.59; p = 0.08
RER 1.06 (0.12) 1.11 (0.12) 1.09 (0.12) F (2, 168) = 2.12; p = 0.12
  1. DBP diastolic blood pressure, dOH delayed orthostatic hypotension during HUT, HR heart rate, NormHRBP normal heart rate and blood pressure response during HUT, POTS postural orthostatic tachycardia syndrome during HUT, RER respiratory exchange ratio, SBP systolic blood pressure, VO2 oxygen consumption in ml/min/kg, VT ventilatory threshold, % VO2 oxygen consumption as percentage of normal values of a population study (19)
  2. #A p-value of < 0.01 was considered significantly different for this study