Fig. 4

Statistical analysis of the drugs associated in gene-drug interactions and PGx information, on 501 patients. Results are indicative of the drug relevance in the sample, based on the frequencies of gene-drug interactions, in the southeastern European population. a Frequency % of gene-drug interactions per drug, deriving from statistical analysis on 501 samples. The deviation bars denote the variations between male and female samples. White: minimum gene-drug interaction; light grey: intermediate gene-drug interaction and dark grey: enhanced gene-drug interaction. b Frequency % of drugs exhibiting enhanced gene-drug interactions (20–100%). c Frequency % of drugs exhibiting intermediate gene-drug interactions (20–100%). d Frequency % of drugs exhibiting minimum gene-drug interactions (20–100%)