Fig. 3

Analysis of the metabolisation activity of the cytochromes on 501 patients. a Reference table listing the categorisation of the allelic forms of each gene with the expected metabolisation efficiency as in ‘ultra-rapid’,’extensive’, ‘intermediate’ and ‘poor’. b, c, d Pie chart of the percentile distribution of the metabolising activity of CYP2C9 (b), CYP2C19 (c) and CYP2D6 (d). Results indicate that 40% to 60% of patients carry at least one CYP gene with altered metabolising efficiency