Fig. 1

Cisplatin induced liver injury in mice. a, b Plasma ALT and AST levels after 24 h cisplatin treatment. c H&E staining and histological score of liver tissue after 24 h cisplatin treatment. d–i mRNA levels of key cytokines and chemokines in the liver. The results are expressed as mean ± SEM. n = 4–10 per group. *P < 0.05. ALT alanine aminotransferase, AST aspartate aminotransferase, H&E Hematoxylin and Eosin