Fig. 5

HDAC4 promotes the proliferation and migration of BSMCs via regulation of the KLF5/Slug/CXCL12 axis. a The expression of HDAC4, KLF5, Slug and CXCL12 as determined by RT-qPCR. b The expression of HDAC4, KLF5, Ac-KLF5, Slug, and CXCL12 as determined by Western blot assay. c The expression of TGF-β and inflammatory factors IL-4, IL-5, and IL-13 in supernatant of BEAS-2B and HBE cells with different treatment as examined by ELISA. d The proliferation of BSMCs with different treatments as examined by CCK-8 assay. e The migration of BSMCs with different treatments as examined by Transwell assay. *p < 0.05 vs. sh-NC or control. #p < 0.05 vs. OVA + sh-NC. & vs. OVA + sh-HDAC4 + vector. These data are measurement data, expressed as mean ± standard deviation. Data among multiple groups were compared using one-way ANOVA, combined with Tukey’s post-hoc tests