Fig. 4

Slug promotes the expression of CXCL12 to promote tinflammation in bronchial epithelial cells and thus induce the proliferation and migration of BSMCs. a The expression of Slug and CXCL12 as determined by RT-qPCR. b The silencing effect of CXCL12 as determined by RT-qPCR. c The silencing effect of CXCL12 as determined by RT-qPCR. d The expression of Slug and CXCL12 in BEAS-2B and HBE cells with different treatments as determined by RT-qPCR. e The expression of TGF-β and inflammatory factors IL-4, IL-5, and IL-13 in supernatant of BEAS-2B and HBE cells with different treatments as examined by ELISA. f The proliferation of BSMCs with different treatments as examined by CCK-8 assay. g The migration of BSMCs with different treatments as examined by Transwell assay. *p < 0.05 vs. sh-NC or control. #p < 0.05 vs. OVA + sh-NC. These data were measurement data, expressed as mean ± standard deviation. Data between two groups were compared using unpaired t-test. Data among multiple groups were compared using one-way ANOVA, combined with Tukey’s post-hoc tests