Fig. 2

Fluorescent distribution characteristics of BMSCs transfected with IL-12 in nude mice. The relative mRNA expression levels of IL-12 in BMSCs were detected and measured following transfection of the IL-12 gene; the IL-12 mRNA expression levels of the IL-12 + BMSC group were significantly higher than those of the blank control group and BMSC group, as shown in a–c. (IL-12: F = 351.261, P < 0.001): n = 3, ^#P < 0.05: Blank control group vs. IL-12 group; ^*P < 0.05: Empty viral vector group vs. the IL-12 group. BMSCs, bone marrow mesenchymal stem cells; IL-12 + BMSC, IL12-lentiviral-transfected BMSC; BMSC group, empty lentiviral vector-transfected BMSC group