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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Antitumor effect of IL-12 gene-modified bone marrow mesenchymal stem cells combined with Fuzheng Yiliu decoction in an in vivo glioma nude mouse model

Fig. 2

Fluorescent distribution characteristics of BMSCs transfected with IL-12 in nude mice. The relative mRNA expression levels of IL-12 in BMSCs were detected and measured following transfection of the IL-12 gene; the IL-12 mRNA expression levels of the IL-12 + BMSC group were significantly higher than those of the blank control group and BMSC group, as shown in ac. (IL-12: F = 351.261, P < 0.001): n = 3, #P < 0.05: Blank control group vs. IL-12 group; *P < 0.05: Empty viral vector group vs. the IL-12 group. BMSCs, bone marrow mesenchymal stem cells; IL-12 + BMSC, IL12-lentiviral-transfected BMSC; BMSC group, empty lentiviral vector-transfected BMSC group

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