Fig. 6

MALAT1 activated the mTOR signaling pathway and EMT of SGC-7901 cells by increasing SRSF1 expression. a Western blot analyses of the extent of mTOR phosphorylation after oe-MALAT1, si-MALAT1, or si-SRSF1 treatment normalized to GAPDH. b Western blot analysis of the expression of E-cadherin, Vimentin, Slug, Snail, and Twist after oe-MALAT1, si-MALAT1, or si-SRSF1 treatment normalized to GAPDH. c Transwell assay displaying the migration of SGC-7901 cells after oe-MALAT1, si-MALAT1, or si-SRSF1 treatment. d Transwell assay displaying the invasion of SGC-7901 cells after oe-MALAT1, si-MALAT1, or si-SRSF1 treatment. * p < 0.05 compared with treatment of si-NC. # p < 0.05 compared with treatment of oe-NC. & p < 0.05 compared with treatment of oe-MALAT1. The values in the figure were all measurement data, expressed as the mean ± standard deviation. Data between multiple groups were analyzed by one-way ANOVA and Tukey's post hoc test. The experiment was repeated for three times independently