Fig. 1

CCL21 was a key gene for GC via prediction using TCGA database. a Expression heatmap of 345 significantly differentially expressed immune genes (red: upregulated genes; green: downregulated genes; red/green scale bar relates to the degree of up/downregulated genes relative to normal samples, expressed as logFoldChange) after differential analysis of STAD dataset in TCGA, wherein N represents normal samples and T represents GC samples. b 33 out of 345 differentially expressed immune genes were significantly related to the GC prognostic risk (p < 0.05, left panel), whose hazard ratio were calculated and plotted at the right panel. c The overall survival curve between patients expressing the high-risk and low-risk genes obtained through the multi-factor Cox model. d The ROC curve used to verify the survival curve