Table 3 The expression of the 8 genes overlapped in top 20 hub genes of derivation cohort and 150 DEGs of validation cohort
From: Cerebrospinal fluid cells immune landscape in multiple sclerosis
Gene symbol | logFC | t | P.Value | adj. P.Val | Up/down-regulated |
|---|---|---|---|---|---|
NLRP3 | − 1.015208 | − 3.717949 | 0.0007216 | 0.0330639 | Down-regulated |
CD86 | − 1.058162 | − 4.334 | 0.0001233 | 0.0212309 | Down-regulated |
C1QB | − 1.146578 | − 3.513766 | 0.0012729 | 0.0415789 | Down-regulated |
LILRB2 | − 1.147991 | − 3.781941 | 0.0006028 | 0.0308922 | Down-regulated |
TLR2 | − 1.245801 | − 4.140113 | 0.0002166 | 0.024029 | Down-regulated |
C1QA | − 1.285648 | − 3.447825 | 0.0015253 | 0.0448478 | Down-regulated |
CSF1R | − 1.331567 | − 4.240982 | 0.0001617 | 0.0222183 | Down-regulated |
IL1B | − 1.447641 | − 3.834274 | 0.0005199 | 0.0292885 | Down-regulated |