Diagnostic performance of Oncuria™, a urinalysis test for bladder cancer

Table 4 Univariate analysis of the three demographic factors and 10 biomarkers in cancers and controls

Variable	Value	Total N	Column %	Cancer N	Row %	OR	LCL	UCL	P
Age	18–54	145	40.1	4	2.8	0.07	0.02	0.23	< 0.0001
Age	55–64	108	29.8	12	11.1	0.31	0.13	0.74	0.009
Age	65–74	64	17.7	17	26.6	0.89	0.38	2.08	0.79
Age	75 +	45	12.4	13	28.9	1.00
Sex	Female	90	24.9	11	12.2	0.94	0.46	1.94	0.86
Sex	Male	271	75.1	35	12.9	1.00
Race	White	101	27.9	31	30.7	7.26	3.71	14.21	< 0.0001
Race	Other	261	72.1	15	5.7	1.00
MMP9 (pg/mL)	< 4,681.7	351	98.3	41	11.7	1.00
M	≥ 4,681.7	6	1.7	5	83.3	37.80	4.31	331.63	0.001
CXCL8/IL8 (pg/mL)	< 3,166.3	355	98.3	42	11.8	1.00
	≥ 3,166.3	6	1.7	4	66.7	14.90	2.65	83.87	0.002
VEGFA (pg/mL)	< 1,837.5	350	98.3	41	11.7	1.00
	≥ 1,837.5	6	1.7	5	83.3	37.68	4.30	330.57	0.001
IX/CA9 (pg/mL)	< 22.429	351	97.5	38	10.8	1.00
	≥ 22.429	9	2.5	8	88.9	65.89	8.02	541.31	0.0001
SDC1 (pg/mL)	< 70,803	357	100.0	46	12.9	1.00
	≥ 70,803	0	0.0
PAI1 (pg/mL)	< 643.76	343	95.5	33	9.6	1.00
	≥ 643.76	16	4.5	12	75.0	28.18	8.60	92.37	< 0.0001
ApoE (pg/mL)	< 9,433.5	339	95.0	31	9.1	1.00
	≥ 9,433.5	18	5.0	15	83.3	49.68	13.63	181.09	< 0.0001
A1AT (pg/mL)	< 337,795	343	96.6	37	10.8	1.00
	≥ 337,795	12	3.4	9	75.0	24.81	6.43	95.75	<0 .0001
ANG (pg/mL)	< 1,951.8	339	95.2	34	10.0	1.00
	≥ 1,951.8	17	4.8	11	64.7	16.44	5.72	47.27	<0 .0001
MM10 (pg/mL)	< 40.975	347	97.2	38	11.0	1.00
	≥ 40.975	10	2.8	7	70.0	18.97	4.71	76.46	< 0.0001

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