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Table 3 Performance of Oncuria™ for bladder cancer detection

From: Diagnostic performance of Oncuria™, a urinalysis test for bladder cancer

Biomarker Area under the curve 95% Confidence interval No. of correctly predicted events No. of correctly predicted nonevents No. of nonevents predicted as events No. of events predicted as nonevents Sen Spec PPV NPV
MMP9 0.78 [0.70 0.86] 30 267 48 15 0.67 0.85 0.38 0.95
CXCL8/IL8 0.82 [0.76 0.88] 33 256 59 12 0.73 0.81 0.36 0.96
VEGFA 0.71 [0.64 0.79] 39 156 159 6 0.87 0.50 0.20 0.96
IX/CA9 0.76 [0.69 0.83] 26 268 47 19 0.58 0.85 0.36 0.93
SDC1 0.55 [0.44 0.66] 45 37 278 0 1.00 0.12 0.14 1.00
PAI1 0.89 [0.83 0.95] 35 283 32 10 0.78 0.90 0.52 0.97
ApoE 0.89 [0.84 0.94] 33 282 33 12 0.73 0.90 0.50 0.96
A1AT 0.82 [0.76 0.88] 33 241 74 13 0.73 0.77 0.31 0.95
ANG 0.84 [0.78 0.90] 38 222 93 7 0.84 0.70 0.29 0.97
MMP10 0.73 [0.64 0.82] 24 292 23 21 0.53 0.93 0.51 0.93
10-biomarker combination 0.93 [0.87 0.98] 39 290 25 6 0.87 0.92 0.61 0.98
10-biomarker combination + 3 demographic features 0.95 [0.90 1.00] 42 292 23 3 0.93 0.93 0.65 0.99