Diagnostic performance of Oncuria™, a urinalysis test for bladder cancer

Table 3 Performance of Oncuria™ for bladder cancer detection

Biomarker	Area under the curve	95% Confidence interval	No. of correctly predicted events	No. of correctly predicted nonevents	No. of nonevents predicted as events	No. of events predicted as nonevents	Sen	Spec	PPV	NPV
MMP9	0.78	[0.70 0.86]	30	267	48	15	0.67	0.85	0.38	0.95
CXCL8/IL8	0.82	[0.76 0.88]	33	256	59	12	0.73	0.81	0.36	0.96
VEGFA	0.71	[0.64 0.79]	39	156	159	6	0.87	0.50	0.20	0.96
IX/CA9	0.76	[0.69 0.83]	26	268	47	19	0.58	0.85	0.36	0.93
SDC1	0.55	[0.44 0.66]	45	37	278	0	1.00	0.12	0.14	1.00
PAI1	0.89	[0.83 0.95]	35	283	32	10	0.78	0.90	0.52	0.97
ApoE	0.89	[0.84 0.94]	33	282	33	12	0.73	0.90	0.50	0.96
A1AT	0.82	[0.76 0.88]	33	241	74	13	0.73	0.77	0.31	0.95
ANG	0.84	[0.78 0.90]	38	222	93	7	0.84	0.70	0.29	0.97
MMP10	0.73	[0.64 0.82]	24	292	23	21	0.53	0.93	0.51	0.93
10-biomarker combination	0.93	[0.87 0.98]	39	290	25	6	0.87	0.92	0.61	0.98
10-biomarker combination + 3 demographic features	0.95	[0.90 1.00]	42	292	23	3	0.93	0.93	0.65	0.99

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